Did you know that your lifestyle can increase your risk of dementia?
What is the Apolipoprotein E gene(ApoE)?
ApoE, located on chromosome 19, is a gene encoding a protein involved in cholesterol transport, with three alleles: ε2, ε3, and ε4. These alleles result in six genotypes (ε2/ε2, ε2/ε3, ε2/ε4, ε3/ε3, ε3/ε4, ε4/ε4), and this polymorphism significantly influences the risk of developing cardiovascular disease and Alzheimer's disease.
The ApoE genotype test, associated with lipid metabolism, can aid in diagnosing and treating hyperlipidemia and identifying at-risk groups."
It is a predisposition test for late-onset Alzheimer's disease, which accounts for 90% of Alzheimer's cases.
Analysis of specific genotypes in the ApoE gene does not guarantee a 100% progression to Alzheimer's disease. It is based on numerous epidemiological studies that certain genotypes can increase the risk of developing Alzheimer's disease.
▲(Sample) Segment of analysis report